ADMINISTRATION
The exact dosage varies depending on the patient's weight, the severity of the condition, and other factors
Administration
- Intravenous infusion, preferably via central venous line
Dose
- 3%: 0.5-2 mL/kg/h by continuous infusion or 250 mL by bolus
- 7.5%: 2-3 mL/kg in 10-15 minutes
- 23.4%: 30 mL in slow bolus (10 minutes)
Infusion rate:
- Bolus: Usually in 10-20 minutes
- Continuous infusion: Adjust according to clinical response and serum sodium levels
GENERAL CONSIDERATIONS
Monitoring:
- Intracranial pressure
- Serum sodium (target: 145-155 mEq/L)
- Serum osmolarity (not to exceed 320 mOsm/L)
- Neurological status
- Water balance
- Kidney and heart function
Caution
Monitor for possible central pontine myelinolysis in rapid corrections of hyponatremia
Avoid in patients with severe hypernatremia
Use with caution in patients with heart or kidney failure
EN 
ES